Aceclofenac is a non steroidal anti-inflammatory drug (NSAID) that is used to reduce pain and inflammation in conditions such as rheumatoid arthritis, osteoarthritis, and ankylosing spondylitis.
It works by blocking the production of certain chemicals in the body that cause pain and inflammation.
Aceclofenac tablets are available in various strengths, typically ranging from 50mg to 200mg.
The usual adult dose is 100mg twice daily, taken with food.
Aceclofenac Tablet Uses
Aceclofenac tablets are used to relieve pain and inflammation associated with various conditions, including:
Rheumatoid arthritis: A chronic inflammatory disorder that affects the joints.
Osteoarthritis: a degenerative joint disease that commonly affects the knees, hips, and hands.
Ankylosing spondylitis: a type of arthritis that primarily affects the spine, causing pain and stiffness.
Musculoskeletal disorders: conditions that affect the muscles, bones, and joints, such as tendonitis, bursitis, and gout.
Acute pain: such as back pain, dental pain, menstrual cramps, and postoperative pain.
How Does Aceclofenac Work in the Body
Aceclofenac is a nonsteroidal anti-inflammatory drug (NSAID) that works by blocking the production of certain chemicals in the body called prostaglandins.
Prostaglandins are involved in causing pain, inflammation, and fever in the body.
Aceclofenac inhibits the activity of the enzyme cyclooxygenase (COX), which is involved in the production of prostaglandins.
By blocking the COX enzyme, aceclofenac reduces the production of prostaglandins, which leads to a reduction in pain, inflammation, and fever.
Aceclofenac is a preferential COX-2 inhibitor, which means it has a higher affinity for the COX-2 enzyme than for the COX-1 enzyme.
This selectivity results in a lower risk of side effects associated with traditional NSAIDs, such as gastrointestinal ulcers and bleeding.
Overall, aceclofenac works by reducing the production of prostaglandins, which helps to relieve pain, inflammation, and fever associated with various conditions.
It is important to take the medication exactly as prescribed by your doctor and not to exceed the recommended dose or duration of treatment.
Aceclofenac Tablet Dose Per Day
Aceclofenac tablets are available in various strengths, typically ranging from 50mg to 200mg.
The recommended dose of aceclofenac tablets may vary depending on the condition being treated and the severity of symptoms.
For adults, the usual dose of aceclofenac is 100mg twice daily, taken with food. The maximum daily dose should not exceed 200mg per day.
For elderly patients or those with renal impairment, the initial dose of aceclofenac may be reduced, and the dose should be adjusted based on the patient’s individual response and tolerability.
It is important to take the medication exactly as prescribed by your doctor and not to exceed the recommended dose or duration of treatment.
Overdosing on aceclofenac can cause serious health problems, such as gastrointestinal bleeding, kidney failure, and liver damage.
If you miss a dose of aceclofenac, take it as soon as you remember.
However, if it is almost time for your next dose, skip the missed dose and continue with your regular dosing schedule.
Do not take a double dose to make up for a missed dose.
Aceclofenac Tablet Side Effects
Like all medications, aceclofenac tablets can cause side effects. Some common side effects of aceclofenac include:
Stomach upset, nausea, and vomiting
Diarrhea or constipation
Headache and dizziness
Skin rash or itching
Increased risk of bleeding
Increased blood pressure
These side effects are usually mild and go away on their own.
However, if they persist or become bothersome, you should consult your doctor.
Rare but serious side effects of aceclofenac may include:
Severe allergic reactions, such as hives, difficulty breathing, and swelling of the face, lips, tongue, or throat
Stomach ulcers or bleeding
Kidney or liver damage
Blood disorders, such as anemia or leukopenia
If you experience any of these serious side effects, seek immediate medical attention.
Aceclofenac may also increase the risk of heart attack or stroke, especially in people who have a history of heart disease or high blood pressure.
It is important to use aceclofenac only as directed by your doctor and to follow all the precautions to minimize the risks of side effects.
Aceclofenac Tablet Interaction
Aceclofenac can interact with other medications and cause adverse effects.
It is important to inform your doctor about all the medications you are taking, including prescription, over-the-counter, and herbal products, to avoid any potential interactions.
Some medications that may interact with aceclofenac include:
Other NSAIDs, such as aspirin or ibuprofen, as this can increase the risk of side effects.
Blood thinners as this can increase the risk of bleeding.
Antihypertensive medications, such as beta-blockers or ACE inhibitors, as this can reduce the effectiveness of these medications.
Diuretics, such as furosemide or hydrochlorothiazide, as this can increase the risk of kidney problems.
Lithium, as this can increase the level of lithium in the blood, leading to toxic effects.
Methotrexate, as this can increase the risk of methotrexate toxicity.
Selective serotonin reuptake inhibitors (SSRIs), as this can increase the risk of bleeding.
Corticosteroids, such as prednisone, as this can increase the risk of gastrointestinal bleeding.
Aceclofenac Tablet for Kidney and Liver Patients
Aceclofenac should be used with caution in patients with kidney or liver problems.
The medication is metabolized in the liver and excreted in the kidneys, so any impairment in these organs can affect the clearance of the drug from the body.
In patients with kidney or liver problems, the dose of aceclofenac may need to be reduced, or the medication may need to be avoided altogether.
Your doctor will assess your kidney and liver function before prescribing aceclofenac and may order regular tests to monitor your kidney and liver function during treatment.
In general, aceclofenac should be used with caution in patients with kidney or liver problems and only under the supervision of a qualified healthcare professional.
It is important to report any symptoms of liver or kidney problems, such as abdominal pain, nausea, vomiting, or changes in urination, to your doctor immediately.
Is Aceclofenac Safe While Breastfeeding and Pregnancy
Aceclofenac is not recommended for use during pregnancy as it may harm the developing fetus, especially during the third trimester.
The medication can also delay labor and delivery and increase the risk of bleeding.
Aceclofenac should only be used during pregnancy if the potential benefits to the mother outweigh the potential risks to the fetus.
Aceclofenac should also be used with caution during breastfeeding as it can pass into breast milk and harm the nursing infant.
It is not known whether aceclofenac can affect milk production or cause other adverse effects in nursing infants.
Women who are breastfeeding should talk to their doctor before using aceclofenac and consider alternative treatments that are safer during breastfeeding.
If you are pregnant, planning to become pregnant, or breastfeeding, you should consult your doctor before using aceclofenac or any other medication to avoid any potential risks to you and your baby.
Your doctor may recommend alternative treatments or adjust the dose of aceclofenac to minimize the risks of adverse effects.
Is Aceclofenac a Strong Painkiller
It is not considered a strong painkiller as it primarily works by reducing inflammation and inhibiting the production of prostaglandins, which are substances in the body that cause pain, fever, and inflammation.
Aceclofenac is typically used to treat mild to moderate pain associated with conditions such as osteoarthritis, rheumatoid arthritis, ankylosing spondylitis, and dental pain.
It is not usually recommended for severe or chronic pain, and is not a substitute for stronger painkillers such as opioids.
If you are experiencing severe or chronic pain, you should talk to your doctor about the best treatment options for your specific condition.
Depending on the cause and severity of your pain, your doctor may recommend stronger painkillers or other treatments to help manage your symptoms.
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